| Children |
| | 1. Clarissa Southworth, b. 15 May 1784, Little Compton, Newport, Rhode Island |
| | 2. Joseph Southworth, b. 1 Jun 1785, Little Compton, Newport, Rhode Island |
| | 3. Hannah Southworth, b. 8 Oct 1786, Little Compton, Newport, Rhode Island |
| | 4. Harriet Southworth, b. 13 Oct 1788, Little Compton, Newport, Rhode Island |
| | 5. Eliza Southworth, b. 10 Jan 1790, Little Compton, Newport, Rhode Island |
| | 6. William Throop Southworth, b. 12 Jul 1791, Little Compton, Newport, Rhode Island |
| | 7. Sarah Southworth, b. 22 Nov 1792, Little Compton, Newport, New York |
| | 8. Mary Southworth, b. 22 Jul 1794, Little Compton, Newport, Rhode Island |
| | 9. Abigail Southworth, b. 2 Jan 1796, Little Compton, Newport, Rhode Island |
| | 10. Rebecca Southworth, b. 27 Sep 1797, Little Compton, Newport, Rhode Island |
| | 11. Constant Southworth, b. 27 Sep 1797, Little Compton, Newport, Rhode Island |
| | 12. Charlotte Southworth, b. 26 Oct 1799, Little Compton, Newport, Rhode Island |
| | 13. Lucy Southworth, b. 28 Jul 1801, Little Compton, Newport, Rhode Island |
| | 14. Lydia Southworth, b. Jan 1803, Little Compton, Newport, Rhode Island |
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